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Control (n = 31)
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Work-related asthma before BD (n = 31)
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Work-related asthma post BD (n = 31)
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Spirometry
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FEV1 (L)
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2.8 ± 0.7
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2.3 ± 0.6**
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2.5 ± 0.7‡‡
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FEV1 (%)
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93.1 ± 15.0
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75.6 ± 19.2***
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81.3 ± 17.4‡‡‡‡
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FVC (L)
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3.5 ± 0.8
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3.1 ± 0.7
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3.3 ± 0.8
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FVC (%)
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95.3 ± 15.1
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84.1 ± 15.0**
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86.6 ± 14.0‡‡
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FEV1/FVC
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79.9 ± 6.7
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72.6 ± 11.7*
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76.4 ± 10.2‡
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FEF 25–75%
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2.9 ± 1.1
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2.0 ± 1.1**
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2.4 ± 1.2
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FEF/CVF
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0.7 ± 0.2
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0.6 ± 0.3
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0.7 ± 0.3
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EPF
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7.1 ± 1.8
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5.5 ± 2.0**
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5.7 ± 2.2
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Plethysmography
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VC (L)
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3.73 ± 0.6
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2.95 ± 0.7***
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3.16 ± 0.6
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IC (L)
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2.45 ± 0.6
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2.69 ± 0.6*
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2.93 ± 0.6‡
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ERV (L)
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1.31 ± 0.08
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0.33 ± 0.2***
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0.26 ± 0.2
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TLC (L)
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5.48 ± 0.9
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5.27 ± 1.1
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5.14 ± 1.3
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TV (L)
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–
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0.86 ± 0.3
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0.87 ± 0.2
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RV (L)
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1.7 ± 0.3
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2.3 ± 0.8***
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2.0 ± 0.9‡
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RV/TLC
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31.11 ± 3.1
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43.8 ± 12.9***
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39 ± 11.6‡
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FRC
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3.02 ± 0.35
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2.86 ± 1.2
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2.3 ± 1.0‡
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TGV
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–
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3.2 ± 1.3
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2.7 ± 1.26‡
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Raw
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1.38 ± 0.09
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5.8 ± 5.2***
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3.7 ± 3.1‡‡
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SGaw
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0.24 ± 0.02
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0.12 ± 0.09***
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0.16 ± 0.1‡
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- Data are mean ± SD; % = percentage of the predicted values
- FEV1: forced expiratory volume in the first second, FVC: forced vital capacity, FEF: forced expiratory flow between 25 and 75% of the FVC, %: percentage of the predicted values, EPF: expiratory peak flow, TLC: total lung capacity, FRC: functional residual capacity, ERV: expiratory reserve volume, RV: residual volume, Raw: airway resistance, TGV: thoracic gas volume, SGaw: specific airway resistance
- *p < 0.05 related to control group
- **p < 0.01 related to control group
- ***p < 0.001 related to control group
- ‡p < 0.05 related to pre-BD
- ‡‡p < 0.01 related to pre-BD
