Fig. 3

The predicted interaction residues on interface of GPVI-10B12. a The key residues on GPVI and b the key residues on 10B12. Red stands for the identified residues via mutagenesis experiments, and blue stands for the key residues which were predicted by MD simulation without mutagenesis data, cyan stands for the dispensable residues demonstrated by mutation data. All interaction residues on interface of GPVI-10B12 complex were predicted here by mean survival ratio, normalized mean rupture time or HBSI index